تاثیر 6 ماه تمرین هوازی با شدت متوسط بر سطوح BDNF، IL-6 و حافظه کوتاه مدت زنان 50- 65 ساله‌ی مبتلا به سندروم متابولیک

Background : The aim of this research was to investigate the effect of six months aerobic exercise with moderate intensity on BDNF, IL-6, and short-term memory in 50-65 years old women with syndrome metabolic. Materials and Methods: 24 women with metabolic syndrome (MetS) took part voluntarily and divided in tow groups MetS exercise (ME), MetS control (MC). ME group participated in an aerobic exercise training (AT) program (six months), tree session per week, each session containing tree performing part and tow rest part (five minutes). Initially, the duration of aerobic exercise in each session was eight minutes. One minute added each week to the duration of aerobic exercise till twelve weeks. Also, blood samples were conducted before and after six months training for evaluating levels of BDNF and IL-6. Short-term memory measured by Digit span memory test, BDNF, and IL-6 measured by Radioimmunoassay before and after six months aerobic training. Data were analyzed using Pearson coefficient, Pried-sample T-Test, and independent samples T-Test. Results: BDNF and short-term memory after six months aerobic exercise significantly increased (P˃0.05). IL-6 after six months aerobic exercise significantly decreased (P˃0.05). Conclusion: Findings show that six months aerobic exercises induce to decrease IL-6 and increase BDNF level, so this trend trepan ameliorate short-term memory score.